The scientific topics of the PEPITES team are pharmacoepidemiology (assessment of drugs and medical devices in real life setting) and healthcare assessment. More precisely, our research concerns high risk populations with specific characteristics (e.g. elderly or ICU patients), benefit risk assessment of biologics in any indication, healthcare assessment with a particular focus on the underlying processes of patient management (e.g. admission, hospital stay strictly speaking, or discharge elements) and its consequences on drug benefit/risk.

Our research is based on the use of field data and healthcare administrative databases or warehouses of in-hospital clinical data, the use or development of several methods, often combined, including patient reported outcomes and e-cohorts for taking the patient perspective into account, various designs for comparative ER and pharmacoepidemiology, systematic reviews and meta-analyses, pragmatic trials, cohorts, case-only designs) and associated statistical modeling / analyses (e.g., causal inference in observational data, modeling of drug exposure, medico-economic evaluation, meta-epidemiological studies).

A large part of our research was endorsed or funded by French health institutions (HAS, OMEDIT, CNAMT, ARS, ANSM, ministry of Health) attesting the interest of public decision-makers for our research and our capacity to translate research into practice and policy.
This multidisciplinary team will involve epidemiologists, biostatisticians, pharmacists and clinicians (gastroenterologists, rheumatologists, geriatricians, dermatologists, intensivists).